Bariatric Surgery Department Sao Luiz Hospital

Laparospopic Bariatric Surgery Theatre Hospital Sao Luiz

Roux en Y Gastric Bypass Surgery

Bariatric Surgical Procedures

Bariatrics deals with the causes, prevention, and treatment of obesity. Bariatric surgery, also known as weight loss surgery, refers to the various baroatric surgical procedures performed to treat obesity by modification of the gastrointestinal tract to reduce nutrient intake and/or absorption.

Introduction to Bariatric Surgery
Bariatric Surgery is a unique field, in that with one operation, a person can be potentially cured of numerous medical diseases including diabetes, hypertension, high cholesterol, chronic headaches, liver disease, sleep apnea and arthritis.

Bariatric Surgery is the only proven method that results in durable weight loss. It avoids the normal failure of dieting. It is a proven surgical approach. The quick recovery with minimally invasive (Laparoscopic) techniques, has increased significant the number of bariatric procedures performed during the last 10 years.

Bariatric surgical procedures can be divided into three kinds:
1. Restrictive procedures decrease food intake and promote a feeling of fullness after meals.
2. Malabsorptive procedures reduce the absorption of calories, proteins and other nutrients.
3. A combination of both restrictive and malabsorptive procedures

Most bariatric procedures can be performed through "open" or "laparoscopic" surgery.
The primary procedures most used for weight loss are:
- Open Gastric Bypass (combination of restrictive and malabsorptive procedures)
- Laparoscopic Gastric Bypass (combination of restrictive and malabsorptive procedures)
- Laparoscopic Adjustable Gastric Banding  - LapBand (restrictive procedure)
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Gastric Bypass - Restrictive and Malabsorptive Bariatric Procedure
Gastric Bypass procedure was developed in the 1960s. The gastric bypass was developed after the weight loss was observed among patients undergoing partial stomach removal for ulcers.

1. Loop Gastric Bypass - later called the Mini Gastric Bypass (MGB)
The first gastric bypass was in 1967, It used a loop of the small bowel for re-construction. Although simple to create, it allowed corrosive juices from the small bowel to enter the gastric pouch, sometimes causing severe inflammation and ulcers. It was abandoned but recently re-employed by a few surgeons, as the "Mini-Gastric-Bypass", mainly to simplify the reconstruction, when performed laparoscopically. Although the mini gastric bypass has a low complication rate, there are now multiple reports in the medical literature of serious long-term complications with the procedure, even requiring revision surgery.

2.Proximal Roux-en-Y Gastric Bypass (RYGBP)
Over several decades, the gastric bypass has been modified into its present form, using a Roux-en-Y limb of intestine connected to a very small stomach pouch which prevents the bile from entering the upper part of the stomach and esophagus. The remaining stomach and first (proximal) segment of small intestine are bypassed.  The Y-intersection is formed near the upper end of the small bowel. The Roux limb is constructed with a length between 30 to 60 inches, preserving most of the small bowel for absorption of nutrients. The patient gets quickly a sense of stomach-fullness, followed by a satiety feeling, shortly after the start of a meal.

The Proximal Roux-en-Y Gastric Bypass (RYGBP) has been the most commonly performed operation for weight loss. Approximately 140,000 gastric bypass procedures have been performed in 2005 in the USA alone. The Roux-en-Y Gastric Bypass outnumbers all other procedures and results.

The amount of intestine bypassed is not enough to create malabsorption of protein or other macronutrients. However, because the bypassed portion of intestine is where the majority of calcium and iron absorption takes place,  lifelong mineral supplementation is mandatory.

The Gastric Bypass has been proven in numerous studies to result in durable weight loss and improvement in weight-related medical illnesses. Half of the weight loss often occurs during the first 6 months after surgery; the weight loss is peaking after 18-24 months. The Gastric Bypass has resulted in marked improvements in quality of life.

The obesity-related illnesses that may be improved or cured after Gastric Bypass surgery include diabetes type II, hypertension, high cholesterol, arthritis, venous stasis disease, bladder incontinence, liver disease, certain types of headaches, heartburn, sleep apnea and many other disorders.

3. Distal Roux-en-Y Gastric Bypass
As the Y-connection is moved farther down the Gastro intestinal tract, the amount of the bowel capable of fully absorbing nutrients is reduced. The Y-connection is made closer to the lower (distal) end of the small bowel, usually 40 to 60 inches from the lower end of the bowel, causing reduced absorption of food, mainly fats and starches, but also various minerals, and fat-soluble vitamins. The unabsorbed fats and starches pass into the large intestine, where bacterial action produces often irritants and malodorous gases.

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Laparoscopic Gastric Bypass (RYGBP) - Restrictive and Malabsorptive Bariatric Procedure (Franco e Rizzi's surgical specialty)
Although the open proximal RYGBP (described above) can be performed with low morbidity and mortality, the wound-related complications such as infection and incisional hernia can be troublesome. Wound infection occurs in as many as 8% of patients after open Gastric Bypass and late incisional hernia occurs in as many as 20% of patients. The laparoscopic approach to Gastric Bypass reduces the postoperative complications arising from a large incision in a obese patient.

In 1994 the first series of laparoscopic Gastric Bypass were performed. The primary differences between Laparoscopic and Open Gastric Bypass are the method of access and method of exposure. Laparoscopic Gastric Bypass is performed through 5 to 6 small abdominal incisions (0.5-2.0 cm) and the abdomen is insufflated with carbon dioxide gas to create space to work. In contrast, Open Gastric Bypass is performed through a larger incision and abdominal wall retractors to create space to work. By reducing the size of the surgical incision and the trauma associated with the operative exposure, the surgical insult has been shown to be much less after laparoscopic surgery compared to open Gastric Bypass. A limitation of the laparoscopic approach is the steep learning curve of this technically challenging procedure for the surgeon, so it is not an operation for the surgeon who has not been trained specifically in this laparoscopic surgery technique.

Advantages of Laparoscopic RYGBP compared to Open RYGBP:
- Lesser operative blood loss
- Shorter hospitalization
- Reduced postoperative pain
- Less pulmonary complications (atelectasis)
- Faster recovery
- Better cosmesis
- Fewer wound complications (incisional hernias and infections)
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Silastic Ring Gastric Bypass - Restrictive and Malabsorptive Procedure
The Silastic® ring gastric bypass is a banded pouch RYGBP. A Silastic® ring is placed around the vertically constructed gastric pouch above the anastomosis between the pouch and intestinal Roux limb. The band controls stomach size by prevention of dilatation of the gastric pouch outlet, and is thought to provide better long-term control of the rate of emptying of the pouch and caloric intake. This procedure also includes placement of a gastrostomy tube for decompression of the distal stomach. A radio-opaque ring marker may be placed around the gastrostomy site to facilitate future percutaneous access to the distal stomach. A small percentage (5%) of patients may have band erosion or obstruction, necessitating surgical band removal.
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Biliopancreatic diversion (BPD) - Malabsorptive procedure
The biliopancreatic diversion (BPD) is a safer malabsorptive alternative to the jejunoileal bypass (JIB) developed in the 1950's. This operation induces controlled malabsorption without many of the potential side effects caused by bacterial overgrowth associated with the JIB.

Unlike the Gastric Bypass where no stomach is removed (only bypassed), the BPD involves the removal of 70% of the stomach. Of note, the portion of the remaining upper stomach is far larger than the small “pouch” created for the RYGBP. This allows patients to eat larger volumes than after a restrictive operation before feeling full (satiety). After entering the upper stomach, food passes through a newly created connection (anastomosis) into the small intestine (alimentary limb). This anatomy is very similar in principle to the standard RYGBP, except that the length of the intestine from the stomach to the colon is much shorter – promoting malabsorption.  Surgeons use various formulas to determine the appropriate length of the alimentary channel and the common channel.
Being a malabsorption operation,  the BPD requires also life-long medical follow-up.
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Duodenal switch (DS) - Malabsorptive procedure
The duodenal switch (DS) is a modification of the BPD designed to prevent ulcers, increase the amount of gastric restriction, minimize the incidence of dumping syndrome, and reduce the severity of protein-calorie malnutrition. However, the dumping syndrome is also believed by many to be a benefit, rather than a detriment, in that it helps patients avoid eating sugary and high fat foods which would adversely affect weight loss.

The DS works through an element of gastric restriction as well as malabsorption. The stomach is fashioned into a small tube, preserving the pylorus, transecting the duodenum and connecting the intestine to the duodenum above where digestive juices enter the intestine. Compared to the BPD, the DS leaves a much smaller stomach that creates a feeling of restriction much like that of a Gastric Bypass. Anatomically, the main difference between the DS and the BPD is the shape of the stomach – the malabsorptive component is essentially identical to that of the BPD. Instead of cutting the stomach horizontally and removing the lower half (such as with the BPD), the DS cuts the stomach vertically and leaves a tube of stomach that empties into a very short (2-4 cm) segment of duodenum.

The duodenum is tolerant of stomach acid and therefore is much more resistant to ulceration compared to the small intestine. Removing part of the stomach also decreases the amount of acid present. Whereas the BPD involves an anastomosis (connection) between the stomach and the intestine, the DS involves an anastomosis between the duodenum and the intestine. The duodenum is cut about 2-4 cm from the stomach (measured from the pyloric valve). The intestine is sewn to the end of the duodenum which remains in continuity with the stomach. The other side of the duodenum will carry all the bile and pancreatic secretions. A theoretical (but clinically unproven) benefit of the DS is an improvement in absorption of iron and calcium in comparison to the BPD. The disadvantage of transecting the duodenum is the large number of vital structures immediately adjacent to the duodenum. Several large blood vessels and the major bile duct are located here. Injury to these structures can be life-threatening.

The DS and BPD procedures have high reported weight loss in long-term studies, but also have the highest rate of nutritional complications compared to the RYGBP and the purely restrictive procedures. These two operations are some of the most complex in bariatric surgery.
Both the BPD and the DS can be performed laparoscopically. However, these operations are more demanding technically than the RYGBP and should only be performed in the most experienced hands.
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Gastroplasty (HG and VBG) - Restrictive Procedure
The gastroplasty (developed in the early 1970s)was designed to be a safer alternative to the RYGBP and the JIB/BPD. The operation itself was made possible by the introduction of mechanical staplers. The Horizontal Gastroplasty (HG) was the first purely restrictive operation performed for the treatment of obesity. The stapling the stomach into a small partition – and only leaving a small opening for food to pass from the upper stomach pouch to the lower one, created the term: stomach stapling. This form of gastroplasty resulted in very poor long-term weight loss and, after several attempted modifications, was abandoned eventually.

The Vertical Banded Gastroplasty (VBG) features a pouch based on the lesser curvature of the stomach and a polypropylene mesh band or Silastic® ring around the outlet of the pouch. The advantages of the VBG include a lower mortality rate and the virtual absence of micronutrient deficiencies.

However, once a popular surgical option for obesity, the VBG is performed less frequently, because studies have shown a prominent rate of weight regain or exacerbation of severe heartburn. Trials have demonstrated superior weight loss with Gastric Bypass compared to VBG. Weight loss for sweets eaters has been shown also to be superior with RYGBP.
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Gastric Banding (GB) - Restrictive Procedure
Another example of a purely restrictive bariatric procedure is the nonadjustable gastric banding. Introduced in 1978 by Wilkinson, a 2 cm Marlex mesh was applied around the upper part of the stomach to separate the stomach into a small upper pouch and a larger bottom pouch. Eventually pouch dilatation resulted in unsatisfactory weight loss.

Later in1980, Molina described the gastric segmentation procedure, in which a Dacron vascular graft was placed around the upper stomach. The gastric pouch was smaller than Wilkinson’s procedure. Because the Dacron graft produced adherence of the liver to the band, it was replaced ultimately by PTFE (Gortex®). Kuzmak began using in 1983 a 1 cm Silicone® band to encircle the stomach, creating a 13 mm stoma and a 30-50 mL proximal gastric pouch.

Advantages of gastric banding:
- Absence of anemia
- Absence of dumping
- Lack of malabsorption
- Short hospital stay
- Very low mortality rate
Complications of gastric banding

- Gastric perforation
- Incisional hernia
- Stomal stenosis
- Band slippage
- Band erosion into stomach
- Need for reversal or revision
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Laparoscopic Adjustable Gastric Banding (LAGB) - Restrictive Procedure
Kuzmak further developed the Gastric Band in 1986 using a Silicone band lined with an inflatable balloon. This balloon was connected to a small reservoir that is placed under the skin of the abdomen through which the diameter of the band can be adjusted. Inflation of the balloon tightens the band and increases weight loss, while deflation loosens the band and reduces weight loss. These bands can be inserted laparoscopically, thereby reducing the complications and discomfort of an open procedure.

The Gastric Banding procedures do not involve an intestinal bypass and induces weight loss solely through the restriction of food intake. For optimal results, strict patient compliance and frequent follow-up for band adjustments are required. LAGB is a reversible procedure that does not carry the risks of nutritional and mineral deficiencies of other bariatric procedures.

Excess weight loss with the laparoscopic adjustable gastric band is lower than that with the gastric bypass or malabsorptive procedures.

Advantages of LAGB - Same as gastric banding
- Adjustability of the band
- Reversibility (by band removal)
- Laparoscopic placement

Complications after LAGB:

Intraoperative:
- Hemorrhage
- Injury to the spleen, stomach, or esophagus
- Conversion to open procedure

Postoperative:
- Band slippage (stomach prolapse)
- Leakage of the balloon or tubing
- Port Infection
- Band infection
- Obstruction
- Nausea and vomiting

Late complications:
- Band erosion into the stomach
- Esophageal dilatation
- Failure to lose weight
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Intragastric Balloon
The intragastric balloon is a silicone prosthesis of spherical format and has a smooth surface. It is introduced into the patient's stomach by an endoscopic procedure, in general there is no need for hospitalization. The risks of complication are low. The mean dwelling time of the balloon in the stomach is from 4 to 6 months. This technique is primarily used for reducing weight in very obese patients (mean of 10-15 kg), who should first lose weight in order to undergo the gastric bypass surgery. It might be used in the less obese who wish to lose weight, and in the obese who do not wish to undergo surgery.

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What is next?
There are other procedures are in development. A implantable gastric stimulation device with small electrodes is attached to the stomach and gives a feeling of fullness when stimulated electrically. The intragastric balloon is now being re-introduced as a simple procedure that can be placed through an endoscope. The balloon will “take up space” and thereby decrease the amount of food patients can eat. Both of these simple procedures do not have yet  documented adequate long-term weight loss. However,  they may have an important role in the future.
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Summary
Almost all above described bariatric surgery procedures have resulted in consistent short-term weight loss. Unfortunately there is no perfect operation. The remarkable drive for the obese patient to regain weight cannot be eliminated in all patients. Furthermore, the history of weight loss surgery repeats itself with procedures that seemed initially to be very promising and safe in theory, but which were later found to be failures. As such, newer procedures should always be viewed with caution. The RYGBP (and also LAGB, DS and BPD) have withstood appropriate scrutiny through well documented results. The Roux-en-Y Gastric Bypass outnumbers all other procedures and results and count almost for 80% of all bariatric surgeries performed worldwide.
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RISK OF BARIATRIC SURGERY
Any major surgery involves the potential for complications - adverse events which increase risk, hospital stay, and mortality. Some complications are common to all abdominal operations, while some are specific to bariatric surgery. A person who chooses to undergo bariatric surgery should know about these risks.
BARIATRIC SURGICAL COMPLICATIONS

 

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